Function of the hypothalamic-hypophysial axis during the post-partum period in ewes and cows

T. M. Nett

doi:10.1530/biosciprocs.9.015

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Bioscientifica Proceedings (2019) 9 RDRRDR15 | DOI: 10.1530/biosciprocs.9.015

REDR1986 Reproduction in Domestic Ruminants (1) (17 abstracts)

Function of the hypothalamic–hypophysial axis during the post-partum period in ewes and cows

T. M. Nett

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Department of Physiology, Colorado State University, Fort Collins, Colorado 80523, U.S.A.

Summary. During pregnancy the hypothalamic–hypophysial axis is suppressed by the high concentrations of progesterone and oestradiol in the circulation. The high concentrations of these steroids appear to inhibit secretion of GnRH from the hypothalamus, resulting in inadequate stimulation of pituitary gonadotrophs to maintain synthesis of LH. This produces a depletion of LH in the anterior pituitary gland that must be restored after parturition before normal oestrous cycles can begin.

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Reproduction in Domestic Ruminants

Society for Reproduction and Fertility

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