Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0019cpr31 | Advancing “-Omics” | CPR2013

Transcriptome analyses of porcine endometrium during the pre-implantation phase

Bauersachs Stefan Bauersachs

The porcine conceptus undergoes rapid differentiation and expansion of its trophoblastic membranes between days 11 and 12 of gestation. The production of estrogen, the porcine embryonic pregnancy recognition signal, by the conceptus increases with trophoblast elongation. A complex interplay of estrogen signaling and prostaglandin (PG) metabolism in the endometrium finally results in prevention of luteolysis. Conceptus attachment to the uterine surface epithelium starts a...

bp0008rdr13 | Peri-implantation: Conceptus-uterine Interaction | REDR2014

Combined analysis of transcriptome studies of bovine endometrium during the preimplantation phase and comparison to results from ovine and porcine preimplantation endometrium

Bauersachs Stefan

Summary. Transcriptome studies of the bovine endometrium during early pregnancy and during the estrous cycle have been performed using DNA microarrays and RNA sequencing to identify genes associated with establishment and maintenance of pregnancy. The results of these studies are reviewed and the identified differentially expressed genes (DEG) are compared to define the overlaps between studies and technical platforms. Good overlaps were found for upregulated ...

bp0007rdr3 | Ruminant Genomes | REDR2010

Creating new knowledge for ruminant reproduction from rapidly expanding and evolving scientific databases

Bauersachs S , Blum H , Krebs S , FröhIich T , Arnold GJ , Wolf E

Declining fertility is a major problem for the dairy industry. Recent developments of Omics-technologies facilitate a comprehensive analysis of molecular patters in gametes, embryos and tissues of the reproductive tract which may help to identify the reasons for impaired fertility. Large Omics-datasets require appropriate bioinformatics analysis in the context of rapidly expanding and evolving scientific databases. This overview summarizes the current status of ruminant genome...

bp0010ised15 | (1) | ISED2019

Embryonic diapause modulates ovarian follicular dynamics and oocyte quality in the European roe deer (Capreolus capreolus)

Bernal-Ulloa SM , Bick JT , van der Weijden VA , Rüegg AB , Drews B , Kowalewski MP , Bauersachs S , Ulbrich SE

The phenomenon of embryonic diapause has been reported to possibly affect ovarian follicular development. The aim of the current study was to identify the impact of the embryonic diapause period on follicle number and oocyte quality in the European roe deer (Capreolus capreolus). In this species, the embryo undergoes five months of developmental delay. We have determined the antral follicle count (AFC), oocyte morphological quality, oocyte meiotic resumption capacity ...