Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0003rdr9 | Development of the Reproductive Axis | REDR1994

The search for the Booroola (FecB) mutation

Montgomery GW , Penty JM , Lord EA , Broom MF

Sheep derived from the Booroola Merino strain carry an autosomal mutation (FecB) that increases ovulation rate and litter size. One approach to characterize the genetic mutation is to locate the gene using positional cloning. The locus has been mapped to a region between genes for secreted phosphoprotein 1 (SPP1) and epidermal growth factor (EGF) on sheep chromosome 6. Analysis of possible candidate genes have excluded a number of genes associated with control of repr...

bp0007rdr10 | Pluripotency in Ruminant Cells | REDR2010

Spermatogonial stem cell biology in the bull: development of isolation, culture, and transplantation methodologies and their potential impacts on cattle production

Oatley JM

Widespread adoption of artificial insemination as a breeding practice has allowed for expanded use of desirable genetics from specific sires and greatly influenced production traits in dairy cattle populations worldwide. In fact, the average dairy cow in the US in 2009 produced 4.5 times more milk than in 1940 when commercialization of artificial insemination began. While many factors have contributed to this rapid increase in levels of milk production, genetic gain through ex...

bp0004rdr30 | Nutrition and Metabolic Signalling | REDR1998

Nutrition and fetal growth: paradoxical effects in the overnourished adolescent sheep

Wallace JM , Bourke DA , Aitken RP

Inappropriate maternal nutrient intake at key developmental timepoints during ovine pregnancy has a profound influence on the outcome of pregnancy and aspects of postnatal productivity. However, the responses to alterations in maternal nutrition in adult sheep are often highly variable and inconsistent between studies. The growing adolescent sheep provides a new, robust and nutritionally sensitive paradigm with which to study the causes, consequences and reversibility of prena...

bp0002rdr16 | Regulation of Folliculogenesis | REDR1990

The ovarian insulin-like growth factor system

Hammond JM , Mondschein JS , Samaras SE , Smith SA , Hagen DR

Abstract unavailableKeywords: ovary; ovarian follicles; granulosa cells; growth factors; insulin-like growth factors© 1991 Journals of Reproduction & Fertility Ltd...

bp0017cpr19 | (1) | CPR2005

Strategies to improve the fertility of frozen-thawed boar semen for artificial insemination

Roca J. , Rodriguez-Martinez H. , Vazquez J.M. , Bolarin A. , Hernandez M. , Saravia F. , Wallgren M. , Martinez E.A.

Although cryopreservation of boar semen for artificial insemination (Al) was developed 35 years ago, cryopreservation conditions and Al strategies are still considered sub-optimal. Al with excessive numbers of frozenthawed sperm (5-6 x 109 cells), still does not achieve fertility levels similar to Al using liquid semen because of reduced sperm survival. Frozenthawed (FT) spermatozoa have therefore not been the preferred option for commercial breeding programme...

bp0018cpr3 | Physiological Roles of The Boar Ejaculate | CPR2009

Optimal characteristics of spermatozoa for semen technologies in pigs

Parrilla I. , Vazquez J.M. , Caballero I. , Gil M.A. , Hernandez M , Roca J. , Lucas X. , Martinez E.A.

Despite the great potential of sperm technologies such as sperm cryopreservation and sperm sex sorting for the improvement of different aspects of swine production, artificial insemination with fresh or stored semen is currently the only sperm technology used at a commercial scale in the pig industry. The lower reproductive performance associated with the use of these sperm technologies is the reason for such limited use. Since optimal characteristics are required for su...

bp0018cpr29 | Control of Prenatal Development | CPR2009

Cellular and molecular events in early and mid gestation porcine implantation sites: a review

Croy B.A. , Wessels J.M. , Linton N.F. , van den Heuvel M. , Edwards A.K. , Tayade C.

Commercial, North American pork breeds (Sus sada) experience significant loss of genetically-normal conceptuses during the peri-implantation (attachment) period and at mid-gestation (day 50 to 90 of the 114 day porcine gestation interval). Although exact causes for these losses are not defined, asynchronous in-utero development and deficits in vascularization of the endometrium and placenta appear to be involved. Understanding of normal maternal-fetal dialogue is critica...