Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0006rdr6 | Nueroendocrinology | REDR2006

Novel concepts about normal sexual differentiation of reproductive neuroendocrine function and the developmental origins of female reproductive dysfunction: the sheep model

Foster DL , Jackson LM , Padmanabhan V

The neuroendocrine regulation of GnRH secretion plays a central role in timing gamete release in both sexes. This regulation is more complex in the female because the discontinuous release of ova is more complex than the continuous release of spermatozoa. This review provides an evolving understanding of the sex differences in reproductive neuroendocrine controls and how these differences arise. The rules for sexual differentiation of steroid feedback control of GnRH secretion...

bp0006rdr8 | Nueroendocrinology | REDR2006

Nutritional inputs into the reproductive neuroendocrine control system - a multidimensional perspective

Blache D , Chagas LM , Martin GB

Evolution has shaped regulatory systems to improve the chance of reproductive success in a somewhat unpredictable environment. One of the more powerful regulators of reproductive function in both sexes is metabolic status, defined as the availability of nutrients and energy to the tissues. Here, we briefly review the basics of the relationship between metabolic status and the activity of the system that controls pulsatile GnRH and LH secretion. We then reflect on these relatio...