Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0010ised7 | (1) | ISED2019

Identification of mink (Neovison vison) fecal proteins during embryonic diapause and placental pregnancy for non-invasive pregnancy diagnosis in wildlife

Curry E , Easley JS , Wojtusik J , Roth TL

Currently, there is no method to diagnose pregnancy non-invasively in most wildlife species that experience delayed implantation and pseudopregnancy, either during embryonic diapause or placental pregnancy. The aim of this study was to utilize farm-raised mink (Neovison vison) as a model species to evaluate changes in the fecal proteome associated with pregnancy. Specific objectives were to: 1) determine if fecal peptides were differentially abundant in parturient ver...

bp0002rdr4 | Maternal Recognition of Pregnancy | REDR1990

Physiological mechanisms of pregnancy recognition in ruminants

Bazer FW , Thatcher WW , Hansen PJ , Mirando MA , Ott TL , Plante C

Summary. Maternal recognition of pregnancy in sheep, cattle and goats involves physiological mechanisms that result in protection of corpora lutea from luteolysis by modification or inhibition of uterine production of luteolytic pulses of prostaglandin (PG) F-2α. Ovine, bovine and caprine luteal cells release oxytocin in a pulsatile manner during late dioestrus. Oxytocin then binds to its endometrial receptors and initiates luteolytic pulses of PGF-2&#945...

bp0004rdr22 | Embryonic Survival | REDR1998

Uterine differentiation as a foundation for subsequent fertility

Bartol FF , Wiley AA , Floyd JG , Ott TL , Bazer FW , Gray CA , Spencer TE

Uterine differentiation in cattle and sheep begins prenatally, but is completed postnatally. Mechanisms regulating this process are not well defined. However, studies of urogenital tract development in murine systems, particularly those involving tissue recombination and targeted gene mutation, indicate that the ideal uterine organizational programme evolves epigenetically through dynamic cell–cell and cell–matrix interactions that define the microenvironmental conte...

bp0006rdr12 | The Eric Lamming Memorial Session | REDR2006

Judge, jury and executioner: the auto-regulation of luteal function

Niswender GD , Davis TL , Griffith RJ , Bogan RL , Monser K , Bott RC , Bruemmer JE , Nett TM

Experiments were conducted to further our understanding of the cellular and molecular mechanisms that regulate luteal function in ewes. Inhibition of protein kinase A (PKA) reduced (P < 0.05) secretion of progesterone from both small and large steroidogenic luteal cells. In addition, the relative phosphorylation state of steriodogenic acute regulatory protein (StAR) was more than twice as high (P&hairsp;<&hairsp;0.05) in large vs small luteal cells. Large steroidogenic...