Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0001redr6 | (1) | REDR1980

The effect of intrauterine gonadectomy on fetal and neonatal gonadotrophin secretion in the lamb

Bremner WJ , Cumming IA , Williams DM , de Kretser DM , Lee VWK

Summary. In Exp. 1, sheep fetuses (2 male and 3 female) were gonadectomized between Days 70 and 120 of gestation and their blood LH and FSH levels were compared to those of control animals (4 male, 6 female) at regular times during the first year after birth. In Exp. 2. fetuses (3 male and 5 female) were gonadectomized between Days 50 and 60 of gestation and gonadotrophin levels at Day 90 of gestation were compared to those of control fetuses of the same age. ...

bp0003rdr14 | Development of the Reproductive Axis | REDR1994

Inhibin and activin in embryonic and fetal development in ruminants

Jenkin G , McFarlane J , de Kretser DM

Inhibin, activin and follistatin are protein hormones with diverse physiological roles. The involvement of inhibin in the regulation of pituitary FSH production and secretion in adult males and non-pregnant females is well established. However, it is unlikely that inhibin plays a similar role in pregnancy in ruminants. Inhibin and activin molecules show a high degree of structural similarity to potent growth and differentiation factors of the transforming growth factor β ...

bp0003rdr35 | Environmental and Metabolic Interactions | REDR1994

Sensory and behavioural control of gonadotrophin secretion during suckling-mediated anovulation in cows

Williams GL , Griffith MK

A major limiting factor in the resumption of postpartum ovarian cycles in cattle is the inhibitory influence of the suckling calf on central regulatory elements controlling the release of GnRH from the median eminence. This inhibitory influence occurs only as a consequence of specifically defined behavioural interactions between the cow and calf in the presence of a maternal bond, cannot be simulated experimentally using thermal, electrical or mechanical stimuli, and is not de...

bp0008rdr10 | Neuroendocrinology | REDR2014

Kisspeptin neuronal networks in pubertal development of domestic female ruminants

Amstalden Marcel , Williams Gary

Summary. The pubertal activation of high-frequency episodic pulses of GnRH is believed to occur as a result of a change in the balance between inhibitory and excitatory stimuli to GnRH neurons. Kisspeptin neurons have been identified as major components of the pathway that regulates GnRH neuronal activity and appear to mediate the effects of estradiol in the control of GnRH secretion. The influence of nutrition on timing the onset of puberty may also involve k...

bp0001redr11 | (1) | REDR1980

Effects of LH-RH infusion, castration and cryptorchidism on gonadotrophin and testosterone secretion in developing rams

Lee VWK , Bremner WJ , Cumming IA , de Kretser DM , Findlay JK

Summary. The relationship between the pituitary gland and testis in rams was studied from birth to sexual maturity. The concentrations of LH, FSH and testosterone increased between 5 and 7 weeks of age; the rise was not correlated with any specific cytological change in the testis. An augmented pituitary response to LH-RH was demonstrated as levels of gonadotrophin increased. It is unclear whether this change in sensitivity plays a role in initiation of the pu...

bp0002rdr13 | Inhibin | REDR1990

Inhibin in rams

Clarke IJ , Tilbrook AJ , Galloway DB , Earl CR , Findlay JK , de Kretser DM

Abstract unavailableKeywords: inhibin; male; reproduction; gonadotrophins; FSH© 1991 Journals of Reproduction & Fertility Ltd...

bp0002rdr11 | Inhibin | REDR1990

Peripheral and intragonadal actions of inhibin-related peptides

Findlay JK , Clarke IJ , Luck MR , Rodgers RJ , Shukovski L , Robertson DM , Klein R , Murray JF , Scaramuzzi RJ , Bindon BM , ’Shea TO , Tsonis CG , Forage RG

Abstract unavailableKeywords: inhibin; activin; follistatin. αN peptide; ovary; follicle; corpus luteum© 1991 Journals of Reproduction & Fertility Ltd...

bp0008rdr1 | Phylogenetics | REDR2014

Ruminant phylogenetics: A reproductive biological perspective

Silvia William J.

Summary. Phylogenetics is the study of evolutionary relationships among species. Phylogenies are based on the comparison of large numbers of characteristics among species. Traditionally, the field of phylogenetics was dominated by paleontologists so the characteristics studied were structural, often skeletal. The field of phylogenetics was revolutionized in the 1980s as scientists began using molecular data, first amino acid, then nucleotide sequences. This le...