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bp0004rdr26 | Local Cellular and Tissue Communication | REDR1998

Roles of extracellular matrix in follicular development

Rodgers RJ , van Wezel IL , Irving-Rodgers HF , Lavranos TC , Irvine CM , Krupa M

The cellular biology and changes in the extracellular matrix of ovarian follicles during their development are reviewed. During growth of the bovine ovarian follicle the follicular basal lamina doubles 19 times in surface area. It changes in composition, having collagen IV α1–26 and laminin α1, ß2 and γl at the primordial stage, and collagen IV α1 and α2, reduced amounts of α3–α5, and a higher content of laminin α1, ß...