Bioscientifica Proceedings

Litter size is often proposed as the trait that could have the greatest impact in improving reproductive efficiency of pigs. Efforts to select directly for increased litter size have generally been unsuccessful and highly variable. As a result, several attempts have been made to identify critical physiological components that control litter size, with the underlying assumption that augmenting these components would improve this important trait. One attempt at improving p...

Summary. Synthesis of biologically active LH is complex, due in part to its hetero-dimeric subunit structure and to the numerous post-translation modifications of each subunit. Through the use of mammalian expression vectors we have been able to introduce the bovine α subunit and LH-β genes into a Chinese hamster ovary cell line deficient in dihydrofolate reductase. The bovine genes are actively expressed and the Chinese hamster ovary cells secrete b...

The physiological mechanisms controlling ovulation rate in mammals involve a complex exchange of endocrine signals between the pituitary gland and the ovary, and a localized exchange of intraovarian hormones between the oocyte and its adjacent somatic cells. The discoveries in sheep of mutations in bone morphogenetic protein 15 (BMP15) and bone morphogenetic protein receptor type IB (BMPR-IB) together with recent findings on the physiological effects of growth differentiation ...

Studies in different animal models and humans give evidence that stress experienced by pregnant mothers affects foetal development and has long-term consequences on many physiological systems and behaviour in the offspring, thus facilitating the risk for disorders later in life. In farm animals, housing conditions or inadequate management practices during gestation may be potential stressors for the mother, which could affect growth, vitality, health and welfare of the d...

Summary. Sexual maturation in cows and ewes is modulated through changes in hypothalamic inhibition. This inhibition results in little or no stimulation of the release of gonadotrophins from the anterior pituitary. The ovary has a primary role in inhibiting gonadotrophin secretion during the prepubertal period and the responsiveness to the negative feedback effects of oestrogen decreases during the peripubertal period. There is also an increased secretion of o...

Keywords: boar exposure; puberty; gilts; pheromones© 1990 Journals of Reproduction & Fertility Ltd...

The second week of pregnancy is a particularly critical period for embryonic survival in pigs. Within that time, conceptus oestrogen synthesis is initiated, spacing and final placement of conceptuses is completed, and the signal for extending the functional lifespan of the corpora lutea is received by the mother. There is also a marked increase in blood flow to the uterus and the uterine endometrium produces and secretes nutrient histotrophe. Coneeptus-derived oestrogen h...

A new method for non-surgical deep intrauterine catheterization of pigs, without sedation of the sow, is described. Insemination results obtained with this method using fresh spermatozoa demonstrate that, in comparison to conventional artificial insemination (Al) (3 × 109 spermatozoa in 80-100 ml), a 20-60-fold reduction in the number of spermatozoa inseminated and at least a 8-10-fold reduction in the dose volume can be used without affecting fertility ...

Abstract unavailable© 2009 Society for Reproduction and Fertility...

Polyspermic fertilization is still a major issue in porcine IVF systems. New information is available to characterize the zona pellucida (ZP) at different developmental stages by scanning electron microscopy (SEM) and by confocal microscopy to show the distribution of ZP glycoproteins. SEM images indicated no differences between in vivo and in vitro matured oocytes; however a change in the surface structure between immature and matured oocytes, as well as between mature ...