Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0018cpr4 | Physiological Roles of The Boar Ejaculate | CPR2009

Recent advances in boar semen cryopreservation

Rath D. , Bathgate R. , Rodriguez-Martinez H. , Roca J. , Strzezek J. , Waberski D.

Since 35 years ago boar semen has been frozen and used for artificial insemination (Al). However, fertility of cryopreserved porcine sperm has consistently been low as boar sperm are more sensitive to cellular stress imposed by changing osmotic balance, oxidative stress, low-temperature exposure, cryo-protectant intoxication etc. and are less able to compensate for these deficiencies at commercially applicable dosages. Additionally, differences in sperm freezability amon...

bp0005rdr32 | Ruminant Models for Human Clinical Medicine | REDR2002

Domestic ruminants as models for the elucidation of the mechanisms controlling ovarian follicle development in humans

Campbell BK , Souza C , Gong J , Webb R , Kendall N , Marsters P , Robinson G , Mitchell A , Telfer EE , Baird DT

It is necessary to understand the basic physiology underlying the complex process of folliculogenesis to address common causes of infertility and to devise innovative strategies to increase the efficiency of assisted reproduction technologies. Availability of suitable ovarian tissue is a major constraint to research in this area in humans, and monovulatory domestic ruminants represent a physiologically relevant model to elucidate basic mechanisms before more focused clinical i...

bp0014cpr8 | Ovarian and Uterine Function | CPR1993

The role of insulin-like growth factors and epidermal growth factor-related peptides in intraovarianregulation in the pig ovary

Hammond J. M. , Samaras S. E. , Grimes R. , Leighton J. , Barber J. , Canning S. F. , Guthrie H. D. ,

The autocrine and paracrine role of the insulin-like growth factors (IGFs) and epiderrnal growth factor (EGF)-related peptides in pig ovary are reviewed. For convenience, each of these regulatory systems is divided into several interactive components: regulated expression of the growth factors, growth factor reception at the cell surface and intracellular action of the growth factors. In addition, the concept of regulated bioavailability and targeting of growth factors in...

bp0016cpr4 | Development of The Follicleand Corpus Luteum | CPR2001

Formation and early development of the corpus luteum in pigs

Murphy B. D. , Gévry N. , Ruiz-Cortés T. , Cote F. , Downey B. R. , Sirois J.

Numerous corpora lutea form from the multiple follicles that ovulate during the oestrous cycle of pigs. Vascular elements invade the follicle from the theca compartment, first centripetally, and subsequently by lateral branching of centripetal veins and arteries. The vessels are the vehicle for dispersion of steroidogenic theca cells throughout the corpus luteum. Mitosis occurs in both the theca and granulosa layers before ovulation, and in luteal cells well into the lut...

bp0005rdr26 | Genes Controlling Reproductive Performance | REDR2002

Prolificacy genes in sheep: the French genetic programmes

Mulsant P , Lecerf F , Fabre S , Bodin L , Thimonier J , Monget P , Lanneluc I , Monniaux D , Teyssier J , Elsen J-M

It has been demonstrated that variations in litter size or ovulation rate in different breeds of sheep can be associated with the segregation of several major genes. This set of natural mutants constitutes a valuable resource to determine key points in the biochemical pathways controlling the development of ovarian follicles. The French genetic programmes were devised to identify two of these genes: the Booroola (FecB) and Lacaune genes. The FecB pro...

bp0008rdr2 | Genomes, Proteomics, Metabolomics | REDR2014

Genetic improvement in cattle — are we sacrificing reproduction in favor of production?

Cushman Robert A , McNeel Anthony K , Tait Jr. Robert G , Lindholm-Perry Amanda K , Perry George A , Snelling Warren M , Bennett Gary L

Summary. Reproductive traits can range from lowly to moderately heritable. Genomic technologies provide a powerful tool for improving selection for traits that are lowly heritable, sex-linked, or not expressed until later in life. Therefore, as genomic technologies become a part of selection decisions, there is a critical need to understand how specific gene variants affect reproductive traits in cattle. Both classical quantitative genetics approaches and geno...

bp0018cpr1 | Physiological Roles of The Boar Ejaculate | CPR2009

The physiological roles of the boar ejaculate

Rodriguez-Martinez H. , Kvist U. , Saravia F. , Wallgren M. , Johannissono A. , Sanz L. , Pena F.J. , Martinez E.A. , Roca J. , Vazquez J.M. , Calvete J.J.

During ejaculation in the boar, sperm cohorts emitted in epididymal cauda fluid are sequentially exposed and resuspended in different mixtures of accessory sex gland secretion. This paper reviews the relevance of such unevenly composed fractions of seminal plasma (SP) in vivo on sperm transport and sperm function and how this knowledge could benefit boar semen processing for artificial insemination (Al). The firstly ejaculated spermatozoa (first 10 ml of the spe...

bp0019cpr16 | Pregnancy, Parturition and The Neonate | CPR2013

Roles of selected nutrients in development of the porcine conceptus during pregnancy

Fuller W. Bazer Fuller W. , Jinyoung Kim Jinyoung , Gwonhwa Song Gwonhwa , Hakhyun Ka Hakhyun , Guoyao Wu Guoyao , Johnson Gregory A. , Vallet Jeffrey L.

Conceptus development in mammals depends on an intra-uterine environment filled with histotroph that includes molecules that are secreted by uterine epithelia and/or selectively transported into the uterine lumen. In pigs, total recoverable glucose, fructose, arginine, leucine and glutamine increase in histotroph with advancing days of the peri-implantation period of pregnancy and in allantoic fluid later in gestation. During pregnancy, the uterine luminal epithelium (LE...