Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0007rdr15 | The Lamming Memorial Lecture | REDR2010

Mechanisms and pathobiology of ovulation

Murdoch WJ , Murphy CJ , Van Kirk EA , Shen Y

The ovulatory process is extraordinary in that it constitutes a hormone- induced injury. Gonadotropin delivered via the follicular vascular wreath stimulates secretion of plasminogen activator by contiguous ovarian surface epithelial cells. A consequent elevation in interstitial plasmin activates collagenases and cleaves tumor necrosis factor α from its anchors on endothelium. Collagen fibril degradation and cellular death at the apex of the preovulatory follicle are hall...

bp0016cpr18 | Gestation and Parturition | CPR2001

Prenatal development as a predisposing factor for perinatal losses in pigs

van der Lende T. , Knol E. F. , Leenhouwers J. I.

The pig industry is confronted with substantial losses due to piglet mortality. With 3-8% stillbirths and generally > 10% preweaning mortality, approximately one fifth of al I fetuses formed fully at the end of gestation die before weaning. Most of these losses occur in the perinatal period. Overall prenatal development (birth weight) and specific prenatal developmental and maturational processes in late gestation are predisposing factors for perinatal losses. Birth weight ...

bp0003rdr4 | Maternal-Embryo Interactions | REDR1994

Cellular interactions during implantation in domestic ruminants

Guillomot M

Implantation is a critical step in the progress of pregnancy, during which the conceptus acquires a fixed position within the uterine lumen, and leads to the establishment of the placental structures. This process implies some cellular modifications of both the uterine epithelium and the trophoblast to ensure cell adhesion between the two tissues. In ruminants, the implantation process is characterized by three main steps: a long pre-attachment period lasting 2–3 weeks d...

bp0001redr5 | (1) | REDR1980

Endocrine control of spermatogenesis in the ram

Courot M , Ortavant R

Summary. In the ram, the size of the testes is related to the concentrations of FSH, LH and testosterone in the blood. A significant linear relationship is observed between testicular size and the level of FSH until a maximum after which no further increase in testis size is observed. Testicular size is also linearly related to the mean level (25 consecutive hours of sampling) of LH and testosterone in the blood, with apparently no upper limit, and to the freq...

bp0008rdr27 | Placentation/Parturition | REDR2014

Evolution of placental structure and function in ruminants

Carter Anthony M

Summary. The defining feature of ruminant placentation is the fusion of binucleate trophoblast cells with uterine epithelium. It was present in the last common ancestor of ruminants and the fusion process is facilitated by the products of endogenous retroviral genes called syncytins. It provides a mechanism to transfer placental hormones to maternal tissues. One of these hormones is placental lactogen, which likewise was present in the ancestral ruminant. An i...

bp0009rdr15 | (1) | REDR1986

Function of the hypothalamic–hypophysial axis during the post-partum period in ewes and cows

Nett T. M.

Summary. During pregnancy the hypothalamic–hypophysial axis is suppressed by the high concentrations of progesterone and oestradiol in the circulation. The high concentrations of these steroids appear to inhibit secretion of GnRH from the hypothalamus, resulting in inadequate stimulation of pituitary gonadotrophs to maintain synthesis of LH. This produces a depletion of LH in the anterior pituitary gland that must be restored after parturition before nor...

bp0015cpr3 | Regulation of Reproductive Function | CPR1997

Control of follicular development and ovulation rate in pigs

Cox Nancy M. ,

There is considerable evidence that nutritional and metabolic control of follicular growth is mediated by metabolic hormones and growth factors, particularly with processes mediated by insulin-like growth factor I (IGF-I) and its binding proteins (IGFBPs). From knowledge that hormones and growth factors which can be affected by diet also positively affect ovarian function, the concept has emerged that metabolic modifiers of gonadotrophin action, rather than gonadotrophins...

bp0010ised15 | (1) | ISED2019

Embryonic diapause modulates ovarian follicular dynamics and oocyte quality in the European roe deer (Capreolus capreolus)

Bernal-Ulloa SM , Bick JT , van der Weijden VA , Rüegg AB , Drews B , Kowalewski MP , Bauersachs S , Ulbrich SE

The phenomenon of embryonic diapause has been reported to possibly affect ovarian follicular development. The aim of the current study was to identify the impact of the embryonic diapause period on follicle number and oocyte quality in the European roe deer (Capreolus capreolus). In this species, the embryo undergoes five months of developmental delay. We have determined the antral follicle count (AFC), oocyte morphological quality, oocyte meiotic resumption capacity ...