Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0005rdr32 | Ruminant Models for Human Clinical Medicine | REDR2002

Domestic ruminants as models for the elucidation of the mechanisms controlling ovarian follicle development in humans

Campbell BK , Souza C , Gong J , Webb R , Kendall N , Marsters P , Robinson G , Mitchell A , Telfer EE , Baird DT

It is necessary to understand the basic physiology underlying the complex process of folliculogenesis to address common causes of infertility and to devise innovative strategies to increase the efficiency of assisted reproduction technologies. Availability of suitable ovarian tissue is a major constraint to research in this area in humans, and monovulatory domestic ruminants represent a physiologically relevant model to elucidate basic mechanisms before more focused clinical i...

bp0013cpr17 | Gamete Physiology | CPR1989

Expression and performance in transgenic pigs

Pursel V. G. , Bolt D. J. , Miller K. F. , Pinkert C. A. , Hammer R. E. , Palmiter R. D. , Brinster R. L.

Summary. Recent research clearly shows that fusion genes can be microinjected into a pronucleus of an ovum and integrate into the pig genome. Animals with such fusion genes are called ‘transgenic’. The percentage of injected ova that developed into transgenic pigs varied among experiments from 0.31% to 1.73%. The percentage of transgenic pigs that expressed the fusion gene ranged from 17% to 100%.Eleven different regulatory s...

bp0016cpr14 | Embryonic and Placental Development | CPR2001

Functional analysis of autocrine and paracrine signalling at the uterine–conceptus interface in pigs

Jaeger L. A. , Johnson L. A. , Ka H. , Gadow J. G. , Burghardt R. C. , Spencer T. E. , Bazer F.W.

The complexity of implantation necessitates intimate dialogue between conceptus and maternal cells, and precise coordination of maternal and conceptus signalling events. Maternal and conceptus-derived steroid hormones, growth factors and cytokines, as well as integrins and their ligands, have important and inter-related roles in mediating adhesion between apical aspects of conceptus trophectoderm and maternal uterine luminal epithelium that leads to formation of an epithelioch...

bp0007rdr31 | Unique Aspects of Reproduction in Diverse Ruminant Species | REDR2010

Assisted reproduction in Mediterranean wild ruminants: lessons from the Spanish ibex (Capra pyrenaica)

Santiago-Moreno J , Coloma MA , Toledano-Díaz A , Castaño C , Gómez-Brunet A , Lopez-Sebastián A

Summary. Despite apparent progress in reproductive technology as applied to wild ruminants, the success achieved in terms of the number of offspring that become healthy adults has remained low. Difficulties often arise through a lack of knowledge regarding appropriate cryopreservation techniques, and indeed through a lack of detailed information on the reproductive physiology of the species in question. The Spanish ibex (Capra pyrenaica) is a wild cap...

bp0017cpr6 | (1) | CPR2005

The role of intra-luteal factors in the control of the porcine corpus luteum

Gadsby J. , Rose L. , Sriperumbudur R. , Ge Z.

In this paper we review three intra-luteal factors and their roles in the corpus luteum (CL). Insulin-like growth factor (IGF)-I, together with its receptor and IGF-binding proteins (IGFBPs), represent an important control system in the CL. IGF-I is a product of small luteal cells and has steroidogenic (i.e. luteotrophic) actions on large luteal cells via the type I receptor, while IGFBPs (e.g. BP-2 and 3; small cells) generally inhibit IGF-Is actions. IGF-I is particula...

bp0011cpr14 | III Pregnancy | CPR1982

Embryo Transplantation and Preservation

Polge C. ,

Abstract unavailable© 1982 The authors...

bp0012cpr7 | Manipulation of The Embryo | CPR1985

How does embryo manipulationfit into present and future pig reproduction?

Polge C. ,

Summary. Available techniques for the collection and direct transplantation of pig embryos are simple and efficient and could be used for the expansion of new lines, for increasing selection pressure in nucleus herds and for extracting healthy stock from a diseased source. However, the reduced viability of pig embryos during culture in vitro and the inability as yet to preserve them by deep-freezing impose limits to the use of embryo transplantat...

bp0012cpr12 | Genetic Factors Influencing Prolificacy | CPR1985

Selection of breeds, strains and individual pigs for prolificacy

Legault C. ,

Summary. Prolificacy, defined as litter size at birth, is currently considered to be the most important component of sow productivity. However, in spite of a spectacular increase in productivity due to management advances, litter size at birth has remained constant for the past 20 years. This situation seems to question the long-term efficiency of the classical methods of genetic improvement such as within-herd selection and crossbreeding between European...