Bioscientifica Proceedings

In mammals, testicular differentiation is initiated by SRY (the sex-determining region of the Y chromosome) gene expression in Sertoli cell precursors, followed by upregulation of the SOX9 gene (SRY-related HMG box gene 9). Subsequently, differentiated testis produces two hormones that induce sexual differentiation of the internal and external genital tract. Knowledge of the molecular mechanisms involved in gonadal differentiation has increased greatly over the past deca...

Litter size is often proposed as the trait that could have the greatest impact in improving reproductive efficiency of pigs. Efforts to select directly for increased litter size have generally been unsuccessful and highly variable. As a result, several attempts have been made to identify critical physiological components that control litter size, with the underlying assumption that augmenting these components would improve this important trait. One attempt at improving p...

Studies in different animal models and humans give evidence that stress experienced by pregnant mothers affects foetal development and has long-term consequences on many physiological systems and behaviour in the offspring, thus facilitating the risk for disorders later in life. In farm animals, housing conditions or inadequate management practices during gestation may be potential stressors for the mother, which could affect growth, vitality, health and welfare of the d...

It is well established that the interferon τ (IFN-τ) family of proteins play a major role in preventing the regression of the corpus luteum during early pregnancy in ruminants, such as cattle, sheep and goats, but not in other mammals. These interferons, which are structurally and functionally related to type I interferon, such as IFN-α and -ω, arose from a duplication of an IFN-ω gene approximately 36 million years ago. The IFN-τ genes have conti...

Development of the corpus luteum (CL) in ruminants occurs in a rapid and time-dependent manner within 1 week after ovulation, with morphologic and biochemical changes in the cells of the theca interna and granulosa cells of the preovulatory follicle. These changes involve luteinisation of steroidogenic cells and angiogenesis to establish normal luteal function (progesterone secretion). The CL is composed of a large number of vascular endothelial cells, large and small steroido...

Summary. The two main types of cellular associations (type I, 2 generations of spermatocytes + 1 of spermatids; type II, 1 of spermatocytes and 2 of spermatids) occupy, respectively, more than half and about a third of the seminiferous epithelium cycle in rams and bulls. However, the duration of the cycle of the seminiferous epithelium and that of spermatogenesis differ between the species. A1 spermatogonia and Sertoli cell total numbers are highly ...

Keywords: oocyte; maturation; meiosis; differentiation; fertilization; pig© 1990 Journals of Reproduction & Fertility Ltd...

There are many potential applications of transgenic methodologies for developing new and improved strains of livestock. One practical application of transgenic technology in pig production is to improve milk production or composition. The first week after parturition is the period of greatest loss for pig producers, with highest morbidity and mortality attributed to malnutrition and scours. Despite the benefits to be gained by improving lactation performance, little prog...

In vitro production (IVP) including in vitro maturation (IVM) and fertilization (IVF) is now an important technology for obtaining live piglets. However, there are still two significant obstacles to the efficient production of viable porcine embryos: (1) polyspermy and (2) fertilization of oocytes arrested at the immature stage. These phenomena relate to production of embryos with abnormal ploidy (polyploidy). To avoid these problems, careful selection of mature oocytes ...

Summary. In four studies secretion patterns of LH, FSH, prolactin, testosterone and progesterone were measured in male and female cattle to determine endocrine changes associated with sexual maturation. Two periods of increasing gonadotrophin secretion were observed, the second one coinciding with puberty. A short luteal phase of 8–12 days precedes the first oestrus at 10–11 or 14 months of age. The testosterone values of the bulls increased with age...