Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0004rdr10 | Comparative Reproductive Function: Implications for Management | REDR1998

Implications of recent advances in reproductive physiology for reproductive management of goats

Chemineau P , Baril G , Leboeuf B , Maurel MC , Roy F , Pellicer-Rubio M , Malpaux B , Cognie Y

The control of reproduction in goats is interesting for technical reasons (synchronization of kiddings, adjustment to forage availability or to economy), and for genetic reasons (identification and dissemination of improved genotypes). The use of short-light rhythms leads to markedly increased production of semen per buck and prevents occurrence of a ‘resting’ season. Recent identification of a bulbourethral lipase in goat spermatozoa opens new perspectives in sperm ...

bp0008rdr16 | Challenges in Optimization of Reproductive Performance | REDR2014

Endocrine disruptors and ovine reproductive development

Lea Richard G , Byers Andrew S , Bellingham Michelle , Cotinot Corinne , Evans Neil , Mandon-Pepin Beatrice , Sinclair Kevin D , Fowler Paul A

Summary. Declining fertility and perturbations in reproductive development in a variety of species have been linked to exposure to endocrine disrupting chemicals (EDCs), which are ubiquitous in the environment. Ruminants are largely exposed to such chemicals in sewage sludge fertiliser widely used in animal production systems. This has been investigated experimentally through the deliberate exposure of pregnant ewes to sewage sludge fertilised pastures or cont...

bp0013cpr17 | Gamete Physiology | CPR1989

Expression and performance in transgenic pigs

Pursel V. G. , Bolt D. J. , Miller K. F. , Pinkert C. A. , Hammer R. E. , Palmiter R. D. , Brinster R. L.

Summary. Recent research clearly shows that fusion genes can be microinjected into a pronucleus of an ovum and integrate into the pig genome. Animals with such fusion genes are called ‘transgenic’. The percentage of injected ova that developed into transgenic pigs varied among experiments from 0.31% to 1.73%. The percentage of transgenic pigs that expressed the fusion gene ranged from 17% to 100%.Eleven different regulatory s...

bp0016cpr14 | Embryonic and Placental Development | CPR2001

Functional analysis of autocrine and paracrine signalling at the uterine–conceptus interface in pigs

Jaeger L. A. , Johnson L. A. , Ka H. , Gadow J. G. , Burghardt R. C. , Spencer T. E. , Bazer F.W.

The complexity of implantation necessitates intimate dialogue between conceptus and maternal cells, and precise coordination of maternal and conceptus signalling events. Maternal and conceptus-derived steroid hormones, growth factors and cytokines, as well as integrins and their ligands, have important and inter-related roles in mediating adhesion between apical aspects of conceptus trophectoderm and maternal uterine luminal epithelium that leads to formation of an epithelioch...

bp0019cpr25 | Reproductive Biotechnology | CPR2013

Genome-wide selection for reproductive traits in swine

McLaren David G , Cleveland Matthew A , Deeb Nader , Forni Selma , Mileham Alan J , Newman Scott , Southwood Olwen I , Wang Lizhen

The introduction of high-density SNP arrays in livestock species has enabled genomic evaluations on a scale not possible just a few years ago. Faster genetic gains are realized from application of genomics in pigs by increasing the accuracy of selection. This is especially important for lowly heritable reproductive traits, where female selection candidates have not yet expressed a phenotype at the point of selection and male candidates have no phenotype at all. Litter si...

bp0019cpr26 | Reproductive Biotechnology | CPR2013

Genome-wide selection for reproductive traits in swine

McLaren David G , Cleveland Matthew A , Deeb Nader , Forni Selma , Mileham Alan J , Newman Scott , Southwood Olwen I , Wang Lizhen

The introduction of high-density SNP arrays in livestock species has enabled genomic evaluations on a scale not possible just a few years ago. Faster genetic gains are realized from application of genomics in pigs by increasing the accuracy of selection. This is especially important for lowly heritable reproductive traits, where female selection candidates have not yet expressed a phenotype at the point of selection and male candidates have no phenotype at all. Litter si...

bp0005rdr9 | Reproductive Technology | REDR2002

Morphological assessment of preimplantation embryo quality in cattle

Maddox-Hyttel P , Gjørret JO , Vajta G , Alexopoulos NI , Lewis I , Trounson A , Viuff D , Laurincik J , Müller M , Tveden-Nyborg P , Thomsen PD

The extensive use of embryo technologies has emphasized the need for assessing embryo quality by morphological techniques, such as transmission electron microscopy, immunocytochemistry for confocal laser scanning microscopy and fluorescence in situ hybridization. By a combination of these techniques, it has been possible to demonstrate: (i) that rRNA gene activation, as monitored by embryonic nucleolar development, is comparable in bovine embryos developed in vivo...

bp0007rdr31 | Unique Aspects of Reproduction in Diverse Ruminant Species | REDR2010

Assisted reproduction in Mediterranean wild ruminants: lessons from the Spanish ibex (Capra pyrenaica)

Santiago-Moreno J , Coloma MA , Toledano-Díaz A , Castaño C , Gómez-Brunet A , Lopez-Sebastián A

Summary. Despite apparent progress in reproductive technology as applied to wild ruminants, the success achieved in terms of the number of offspring that become healthy adults has remained low. Difficulties often arise through a lack of knowledge regarding appropriate cryopreservation techniques, and indeed through a lack of detailed information on the reproductive physiology of the species in question. The Spanish ibex (Capra pyrenaica) is a wild cap...

bp0008rdr2 | Genomes, Proteomics, Metabolomics | REDR2014

Genetic improvement in cattle — are we sacrificing reproduction in favor of production?

Cushman Robert A , McNeel Anthony K , Tait Jr. Robert G , Lindholm-Perry Amanda K , Perry George A , Snelling Warren M , Bennett Gary L

Summary. Reproductive traits can range from lowly to moderately heritable. Genomic technologies provide a powerful tool for improving selection for traits that are lowly heritable, sex-linked, or not expressed until later in life. Therefore, as genomic technologies become a part of selection decisions, there is a critical need to understand how specific gene variants affect reproductive traits in cattle. Both classical quantitative genetics approaches and geno...