Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0013cpr17 | Gamete Physiology | CPR1989

Expression and performance in transgenic pigs

Pursel V. G. , Bolt D. J. , Miller K. F. , Pinkert C. A. , Hammer R. E. , Palmiter R. D. , Brinster R. L.

Summary. Recent research clearly shows that fusion genes can be microinjected into a pronucleus of an ovum and integrate into the pig genome. Animals with such fusion genes are called ‘transgenic’. The percentage of injected ova that developed into transgenic pigs varied among experiments from 0.31% to 1.73%. The percentage of transgenic pigs that expressed the fusion gene ranged from 17% to 100%.Eleven different regulatory s...

bp0005rdr23 | Neuroendocrine Interactions | REDR2002

Origin of cerebrospinal fluid melatonin and possible function in the integration of photoperiod

Tricoire H , Møller M , Chemineau P , Malpaux B

Melatonin, which is synthesized at night by the pineal gland, is present in the cerebrospinal fluid (CSF), but its entry site and its role in this compartment are not known. Using several approaches, we tested the hypothesis that melatonin enters the CSF through the pineal recess, an evagination of the third ventricle. CSF melatonin concentrations are higher near the pineal gland than in the anterior part of the third ventricle, and decrease markedly (80%) after sealing of...

bp0009rdr9 | (1) | REDR1986

Spermatogenesis and Sertoli cell numbers and function in rams and bulls

Hochereau-de Reviers M. T. , Monet-Kuntz C. , Courot M.

Summary. The two main types of cellular associations (type I, 2 generations of spermatocytes + 1 of spermatids; type II, 1 of spermatocytes and 2 of spermatids) occupy, respectively, more than half and about a third of the seminiferous epithelium cycle in rams and bulls. However, the duration of the cycle of the seminiferous epithelium and that of spermatogenesis differ between the species. A1 spermatogonia and Sertoli cell total numbers are highly ...

bp0013cpr14 | Gamete Physiology | CPR1989

Maturation of pig oocytes in vivo and in vitro

Moor R. M. , Mattiolit M. , Ding J. , Nagai T.

Keywords: oocyte; maturation; meiosis; differentiation; fertilization; pig© 1990 Journals of Reproduction & Fertility Ltd...

bp0013cpr20 | Early Pregnancy | CPR1989

Regulation of uterine and conceptus secretory activity in the pig

Simmen R. C. M. , Simment R. C. M. ,

Summary. Evidence is presented for the involvement of a number of specific uterineand conceptus-derived proteins in endometrial differentiation and conceptus or feml development. These secretory proteins include mitogens (insulin-like growth factor-I and -II, epidermal growth factor, uterine lumina] fluid mitogen). binding and transport proteins (uteroferrin, insulin-like growth factor and retinal binding proteins, respectively), protease inhibitors (anti...

bp0015cpr1 | Regulation of Reproductive Function | CPR1997

Role of neuropeptides and amino acids in controlling secretion of hormones from the anterior pituitary gland in pigs

Estienne M. J. , Harter-Dennis M. J. , Barb C. R.

All reproductive processes involve one or more of the protein hormones secreted from the anterior pituitary gland: LH, FSH, prolactin, growth hormone, ACTH and thyroidstimulating hormone (TSH). Primary hormones of reproduction, such as LH and FSH, directly regulate a reproductive activity. For example, LH and FSH stimulate follicular growth and the associated secretion of oestradiol in sows. In contrast, secondary hormones of reproduction such as TSH are permissive and re...

bp0016cpr23 | New Technologies | CPR2001

Transgenic alteration of sow milk to improve piglet growth and health

Wheeler M. B. , Bleck G. T. , Donovan S. M.

There are many potential applications of transgenic methodologies for developing new and improved strains of livestock. One practical application of transgenic technology in pig production is to improve milk production or composition. The first week after parturition is the period of greatest loss for pig producers, with highest morbidity and mortality attributed to malnutrition and scours. Despite the benefits to be gained by improving lactation performance, little prog...