Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0005rdr34 | Ruminant Models for Human Clinical Medicine | REDR2002

The differential secretion of FSH and LH: regulation through genes, feedback and packaging

McNeilly AS , Crawford JL , Taragnat C , Nicol L , McNeilly JR

While the role of oestradiol and progesterone in the control of GnRH pulsatile secretion and generation of the preovulatory GnRH surge to induce release of the LH surge has been fully investigated, less attention has been given to changes in the pituitary gland that may sensitize gonadotrophs to switch from pulsatile release to surge release of LH, in particular. Furthermore, in the follicular phase while pulsatile secretion of LH is maximal, FSH secretion is reduced, yet both...

bp0008rdr22 | Oocyte and Follicle | REDR2014

The metabolism of the ruminant cumulus-oocyte complex revisited

Thompson Jeremy G , Gilchrist Robert B , Sutton-McDowall Melanie L

Summary. The progress in understanding the metabolism of the ruminant cumulus-oocyte complex (COC) from large antral follicles has progressed significantly in the past decade. In particular, new insights in the importance of lipid metabolism, ß-oxidation and its relationship to oxidative phosphorylation within oocytes have emerged. This provides opportunities for tapping into the potential yield of ATP from lipid metabolism, as ATP content is a major dete...

bp0013cpr2 | The Hypothalamic-Pituitary-Ovarian Axis | CPR1989

Regulation and action of gonadotrophinsin pigs

Esbenshade K. L. , Ziecikt A. J. , Britt J. H.

Summary. Gonadotrophins, synthesized and secreted from the basophils of the adenohypophysis, bind to various target cells and elicit a wide variety of responses. Specific receptors for gonadotrophins have been found on plasma membranes of thecal, granulosa, luteal, endometrial and myometrial cells in the female and on Leydig and Sertoli cells in the Male. Gonadotrophins exert their effects through various intracellular second messengers and control biosyn...

bp0014cpr9 | Ovarian and Uterine Function | CPR1993

Sources and biological actions of relaxin in pigs

Bagnell C. A. , Zhang Q. , Downey B. , Ainsworth L.

Although the major source of relaxin in pigs is the corpus luteum of pregnancy, there is now evidence for relaxin gene expression and translation into protein in the theca intema cells of the preovulatory follicle, the corpus luteum of the cycle and the uterus. The theca interna cells retain their ability to express the relaxin gene and protein following ovulation. During the early stages of development of the corpus luteum, the theca-derived small lutein cells are the so...

bp0016cpr14 | Embryonic and Placental Development | CPR2001

Functional analysis of autocrine and paracrine signalling at the uterine–conceptus interface in pigs

Jaeger L. A. , Johnson L. A. , Ka H. , Gadow J. G. , Burghardt R. C. , Spencer T. E. , Bazer F.W.

The complexity of implantation necessitates intimate dialogue between conceptus and maternal cells, and precise coordination of maternal and conceptus signalling events. Maternal and conceptus-derived steroid hormones, growth factors and cytokines, as well as integrins and their ligands, have important and inter-related roles in mediating adhesion between apical aspects of conceptus trophectoderm and maternal uterine luminal epithelium that leads to formation of an epithelioch...

bp0005rdr23 | Neuroendocrine Interactions | REDR2002

Origin of cerebrospinal fluid melatonin and possible function in the integration of photoperiod

Tricoire H , Møller M , Chemineau P , Malpaux B

Melatonin, which is synthesized at night by the pineal gland, is present in the cerebrospinal fluid (CSF), but its entry site and its role in this compartment are not known. Using several approaches, we tested the hypothesis that melatonin enters the CSF through the pineal recess, an evagination of the third ventricle. CSF melatonin concentrations are higher near the pineal gland than in the anterior part of the third ventricle, and decrease markedly (80%) after sealing of...

bp0009rdr9 | (1) | REDR1986

Spermatogenesis and Sertoli cell numbers and function in rams and bulls

Hochereau-de Reviers M. T. , Monet-Kuntz C. , Courot M.

Summary. The two main types of cellular associations (type I, 2 generations of spermatocytes + 1 of spermatids; type II, 1 of spermatocytes and 2 of spermatids) occupy, respectively, more than half and about a third of the seminiferous epithelium cycle in rams and bulls. However, the duration of the cycle of the seminiferous epithelium and that of spermatogenesis differ between the species. A1 spermatogonia and Sertoli cell total numbers are highly ...

bp0013cpr14 | Gamete Physiology | CPR1989

Maturation of pig oocytes in vivo and in vitro

Moor R. M. , Mattiolit M. , Ding J. , Nagai T.

Keywords: oocyte; maturation; meiosis; differentiation; fertilization; pig© 1990 Journals of Reproduction & Fertility Ltd...